What is Tresiba?
tresiba insulin is a long-acting basal insulin called insulin. It is used in adults, adolescents, and children 1 year of age and older to treat diabetes mellitus. Tresiba helps the body to lower blood sugar levels. It is used once a day. When the usual administration time cannot be followed, the administration time can be varied because Tresiba has a prolonged hypoglycemic effect.
How does it work?
Insulin specifically binds to the human insulin receptor and produces the same pharmacological effects as insulin.
The hypoglycemic effect of insulin is due to the fact that it facilitates the absorption of glucose by binding to insulin receptors in muscle and fat cells, and at the same time that it inhibits hepatic glucose production.
What are the benefits of taking it?
Tresiba can be used with fast-acting insulins administered in conjunction with meals. In patients with type 2 diabetes mellitus, Tresiba can be used in combination with diabetes tablets or injectable antidiabetics other than insulin. In patients with type 1 diabetes mellitus, Tresiba should always be used in combination with fast-acting insulins administered in conjunction with meals.
How do I use it and its dosage?
Always use this medicine exactly as your doctor has told you. If in doubt, ask your doctor, pharmacist, or nurse again.
If you are blind or have low vision and cannot read the dose counter on the pen, do not use this pen without assistance. Ask a person who is vision impaired and trained in the use of the FlexTouch pre-filled pen for help.
Tresiba is a pre-filled pen is available in two doses. “Tresiba 100 units/ml” or “Tresiba 200 units/ml” which is clearly indicated on the pen label and on the carton. In addition, the Tresiba 100 unit/ml carton and label are light green and the Tresiba 200 unit/ml carton and label are dark green with stripes and a red box highlighting the dose.
For both doses, the required dose is selected in units. However, the dose units vary between the two Tresiba doses.
The 100 unit/ml pre-filled pen can provide a dose of 1–80 units in one injection, in increments of 1 unit. The dose counter on the pre-filled pen shows the number of units of insulin to inject. Do not make any dose calculations.
Your doctor will decide together with you: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............. ........................
- how much Tresiba you will need each day;
- when to check your blood sugar level and if you need a higher or lower dose.
Flexibility in the administration schedule
- Always follow your doctor’s recommendations for use.
- Use Tresiba once a day, preferably at the same time every day.
- Sometimes, when it is not possible to use Tresiba at the same time of day, you can use Tresiba at a different time of day. Make sure that a minimum of 8 hours pass between doses. There is no experience with the flexibility of the Tresiba administration schedule for children and adolescents.
- If you want to change your usual diet, consult your doctor, pharmacist or nurse first, since a change in diet can alter your need for insulin.
How to inject
- Tresiba is injected under the skin (subcutaneous injection). Do not inject it into a vein or muscle.
- The best injection sites are the front of the thigh, the upper arm, and the front of the waist (abdomen).
- Change the place inside the injection site every day to reduce the risk of developing skin bumps and depressions.
- Always use a new needle with each injection. Reusing needles may increase the risk of needle lockout, leading to inaccurate dosing. Dispose of the needle safely after each use.
- Do not use a syringe to withdraw the solution from the pen to avoid dosing errors and possible overdose.
Side effects & precautions
Like all medicines, this medicine can cause side effects, although not everybody gets them.
When being treated with insulin, hypoglycemia (too low a blood sugar level) can occur very frequently (may affect more than 1 in 10 people). It can be very serious. If your blood sugar level drops too low you may lose consciousness. Severe hypoglycemia can damage the brain and be life-threatening. If you have symptoms of low blood sugar, take steps to raise your blood sugar level immediately.
If you experience a severe allergic reaction (rarely appear) to insulin or any of the components of Tresiba, stop treatment with Tresiba, and see your doctor immediately. The signs of a serious allergic reaction are:
- local reactions spread to other parts of the body;
- suddenly feel sick with sweating;
- begins to feel dizzy (vomiting);
- you experience shortness of breath;
- you have palpitations or feel dizzy.
Common (may affect up to 1 in 10 people)
Local reactions: localized reactions may occur at the injection site. Symptoms may include pain, redness, hives, swelling, and itching. These reactions usually disappear after a few days. If symptoms do not disappear after a few weeks, see your doctor. If reactions worsen, stop Tresiba treatment and see a doctor immediately.
Uncommon (may affect up to 1 in 100 people)
Skin changes at the injection site (lipodystrophy): Fat tissue under the skin can be reduced (lipoatrophy) or increased (lipohypertrophy). Changing the injection site each time you inject can reduce the risk of developing these skin changes. If you notice these changes on your skin, talk to your doctor or nurse. If you continue to inject at the same place, these reactions can worsen and affect the amount of medication your body absorbs.
Inflammation of the joints: When you start using the medicine, the body may retain more fluid than it should. This causes inflammation of the ankles and other joints. This effect usually disappears quickly.
Rare (may affect up to 1 in 1,000 people)
This medicine can cause allergic reactions like hives, swelling of the tongue and lips, diarrhea, nausea, tiredness, and itching.
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