Qlaira is a contraceptive that is used to prevent pregnancy. Qlaira is used in the treatment of excessive menstrual bleeding (not caused by any disease of the uterus) in women who want to use oral contraception. Each colored active tablet contains a small number of female hormones: estradiol valerate, or estradiol valerate combined with dienogest. The 2 white tablets do not contain active substances and are called inactive tablets. The dark yellow pills contain 3mg of estradiol valerate. The intermediate red pills contain 2mg of estradiol valerate and 2mg of dienogest. The light yellow pills contain 2mg of estradiol valerate and 3mg of dienogest. The dark red pills contain 1mg of estradiol valerate.

What is Qlaira?

Qlaira is a birth control pill that contains two female hormones, a progestogen called Dienogest and a natural estrogen called Estradiol Valerate, in different concentrations. This medicine has the characteristics that it offers the user a more regular menstrual cycle, providing less painful menstruation and lighter bleeding. In addition, Qlaira comes in a package of 28 pills.

Qlaira is a contraceptive more similar to a woman’s menstrual cycle, and the color of each pill indicates the different concentrations of progestogen, estrogen, or both. The 26 colored pills contain hormones and the 2 white pills contain no hormones.

  • The dark yellow pills contain 3mg of estradiol valerate.
  • The intermediate red pills contain 2mg of estradiol valerate and 2mg of dienogest.
  • The light yellow pills contain 2mg of estradiol valerate and 3mg of dienogest.
  • The dark red pills contain 1mg of estradiol valerate.
  • White pills do not contain hormones.

How does it work?

Qlaira is a pill that is used in the prevention of pregnancy. The active compounds are synthetic hormones, which simulate the action of progesterone and estrogen. These oral contraceptives can also relieve symptoms of heavy periods such as pain and excessive bleeding. Its presence helps convince the body that ovulation has already occurred and does not need to take place. This results in the cessation of the production and release of the egg, and in which the quality of the endometrium is modified so that it cannot receive the egg. Sperm motility is also slowed by these agents, through the thickening of vaginal mucus.

What are the benefits of taking it?

Qlaira is indicated for women as a contraceptive pill and as a treatment for heavy menstrual bleeding, in women of childbearing age and who do not have a contraindication to using combined oral contraceptives.

How do I use it and its dosage?

The tablets should be taken orally, in the order indicated on the package, every day at approximately the same time, with a little liquid if necessary. The taking of tablets is continuous. One tablet should be taken daily for 28 consecutive days. Each new pack starts the day after finishing the last tablet in the previous calendar pack. Bleeding from deprivation usually begins during the taking of the last tablets in the calendar pack and may not have ended before starting the next calendar pack. In some women, bleeding begins after taking the first few tablets from the new calendar container.

Side effects & precautions

Like all medicines, this medicine can cause side effects, although not all people suffer from them.

The following side effects have been related to the use of Qlaira:

Common side effects: may affect up to 1 in 10 people

  • headache
  • abdominal pain, nausea
  • acne
  • absence of periods, breast discomfort, painful periods, irregular bleeding (irregular and heavy bleeding)
  • weight gain

Uncommon side effects: may affect up to 1 in 100 people

  • yeast infections, yeast infection of the vulva and vagina, vaginal infection
  • increased appetite
  • depression, depressive mood, emotional disorders, sleep disorder, lack of sex drive, mental disorder, mood swings
  • dizziness, migraine
  • hot flashes, high blood pressure
  • diarrhea, vomiting
  • increased liver enzymes
  • hair loss, excessive sweating (hyperhidrosis), itching and a rash
  • muscle cramps
  • enlargement of the breasts, lumps in the breasts, abnormal growth of cells on the cervix (cervical dysplasia), uterine genital bleeding, painful sexual intercourse
  • fibrocystic breast disease, heavy menses, disorders
  • periods, ovarian cyst, pelvic pain, premenstrual syndrome, growth in the uterus, uterine contractions, uterine/vaginal bleeding incl. spotting, vaginal discharge, vulvovaginal dryness
  • fatigue, irritability, inflammation of parts of the body, eg the ankles (edema)
  • weight loss, changes in blood pressure

Rare side effects: may affect up to 1 in 1,000 people

  • candida infection, oral herpes, pelvic inflammatory disease, vascular disease of the eye that looks like a fungal infection (suspected histoplasmosis syndrome eye), fungal skin infection (tinea versicolor), urinary tract infection
  • inflammation by bacteria in the vagina
  • fluid retention, increase in some fats in the blood (triglycerides)
  • aggression, anxiety, a feeling of unhappiness, increased interest in sex, nervousness,
  • nightmares, restlessness, sleep disorders, stress
  • decreased attention, pins and needles, vertigo
  • intolerance to contact lenses, dry eyes, eye swelling
  • heart attack (myocardial infarction), palpitations
  • bleeding from varicose veins, blood clot in a vein (venous thromboembolism),
  • low blood pressure, inflammation of superficial veins, painful veins
  • constipation, dry mouth, indigestion, heartburn
  • nodules in the liver (focal nodular hyperplasia), chronic inflammation of the gallbladder
  • allergic skin reactions, golden brown spots (chloasma) and other disorders
  • pigmentation, male-patterned hair growth, excessive growth of the hair, skin conditions such as dermatitis and neurodermatitis, dandruff and oily skin (seborrhea) and other skin disorders
  • back pain, jaw pain, feeling of heaviness
  • pain in the urinary tract
  • abnormal withdrawal bleeding benign breast nodules, stage breast cancer
  • early, cysts in the breast, discharge from the breast, polyp in the cervix,
  • redness of the cervix, bleeding during intercourse, discharge
  • spontaneous milk, genital discharge, less abundant menses, delayed menses, rupture of an ovarian cyst, vaginal odor, burning sensation in the vulva and vagina, vulvovaginal discomfort
  • inflammation of lymph nodes
  • asthma, shortness of breath, nosebleeds
  • chest pain, tiredness and a general feeling of being unwell, fever
  • abnormal cervical smear


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