Rozex contains the active ingredient metronidazole, which kills bacteria. This medicine is applied to the skin. The gel soothes the skin so that inflammatory reactions are completely relieved or disappear. Rozex requires a prescription. This medication was developed specifically for the treatment of rosacea, a skin condition characterized by red spots on the cheeks, nose, forehead, and/or chin. Sometimes pustules or papules develop in the affected areas or blood vessels in the skin are visible. Rosacea is not curable; With metronidazole, however, symptoms can be effectively suppressed. Rozex is also sometimes prescribed for other skin infections

What is Rozex?

Rozex cream and gel are used to treat a skin condition known as rosacea. They use the active substance called metronidazole which belongs to the family of medicines of anti protozoa and antibiotics. This topical substance is applied directly to the affected area of the skin to kill bacteria and reduce inflammation. The Rozex cream and gel ingredients include: Rozex Gel 0.75% contains: 7.5 mg of metronidazole (D.C.I.) per gram. Topical Gel. Rozex Gel is indicated in the treatment of inflammatory papules, pustules, and acne rosacea erythema.

How does it work?

Metronidazole is an antibacterial and antiprotozoal agent active against a large number of pathogenic microorganisms. The mechanism of action of metronidazole in the treatment of acne rosacea is unknown, but there is evidence to suggest that it could be due to its antibacterial and/or anti-inflammatory properties.

What are the benefits of taking it?

The active substance in Rozex gel is metronidazole, which is a type of medicine that kills bacteria. It is for topical use. Rozex gel treatment calms the skin and greatly reduces skin inflammation, in some cases eliminating it completely. Rozex gel is only available by prescription. Rozex gel has been specifically designed for the treatment of rosacea, a skin condition that manifests itself in the form of redness in areas of the face, especially on the cheeks, nose, forehead and/or chin, and that sometimes it is accompanied by visible bumps, spots and red veins on the skin. There is currently no known cure for rosacea, but treatment with metronidazole can control the symptoms. Rozex can also be prescribed to treat other skin infections.

How do I use it and its dosage?

Follow exactly the Rozex gel administration instructions indicated by your doctor. Ask your doctor or pharmacist if you have doubts.

Apply the gel to the affected areas twice a day, in the morning and at night before going to bed.

  1. Before applying the gel, clean the affected area with a mild cleanser and dry the affected area
  2. Apply a thin layer of gel
  3. Massage lightly
  4. After the application, you should wash your hands carefully.

You can use non-comedogenic (pimple-producing) and non-astringent (non-drying) cosmetics after the application of Rozex Gel.

Use in children

Do not use in children. There is no experience in the use of this medicine in children.

Side effects & precautions

Like all medicines, Rozex gel for Rosacea can cause side effects, although not everybody gets them. This medication may occasionally cause unwanted side effects at the application site such as:

Common side effects (may affect up to 1 in 10 people)

  • Dry Skin
  • Erythema (redness of the skin)
  • Pruritus (itchy skin)
  • Skin discomfort (burning, pain/stinging)
  • Skin irritation
  • Worsening rosacea (disease of the central part of the face consisting of redness and itching of the cheeks and chin)

Rare side effects (may affect up to 1 in 1,000 patients)

  • Hypoaesthesia (decreased sensitivity)
  • Paresthesia (impaired sensitivity)
  • Dysgeusia (alteration of taste to metallic taste)
  • Sickness

Adverse effects of Unknown frequency (frequency cannot be estimated from the available data)

  • Contact dermatitis (eczema from contact with the gel)

Special warnings and precautions

Contact with the eyes and mucous membranes should be avoided. Some cases of ocular tearing have been described in connection with the use of topical metronidazole, therefore the products should not be contacted with the eyes.

In the event of local irritation, the frequency of application should be reduced or treatment should be temporarily or permanently discontinued, according to clinical criteria.

Cosmetics can be used after the application of Rozex.

Metronidazole belongs to the chemical family of nitroimidazoles, so it should be used with caution in those patients who suffer or have a history of blood dyscrasias.

Exposure to UV radiation (sunbaths, solarium, sunlamps) should be avoided during treatment with metronidazole.

Unnecessary and prolonged use of this medicine should be avoided. Evidence suggests that metronidazole is carcinogenic in certain animal species. There is no evidence of data on the carcinogenic effect in humans.

Methyl parahydroxybenzoate (E-218) can cause allergic reactions (possibly delayed). Rozex gel can cause skin irritation because it contains propylene glycol.


Interactions with other drugs are less likely with topical administration of metronidazole, but its co-prescription with anticoagulants should be considered. Oral administration of metronidazole has been reported to interact with disulfiram, alcohol (Antabuse effect) and may potentiate the anticoagulant effect of Coumarin and Warfarin, resulting in prolonged prothrombin time. The effect of topical metronidazole on prothrombin is unknown.


There are no reviews yet.

Be the first to review “Rozex”

Your email address will not be published. Required fields are marked *

Shopping Cart
Scroll to Top