Skinoren Cream


Skinoren is a treatment that works against bacteria to fight acne. It is applied to the skin twice a day

What is Skinoren?

skinoren cream belongs to the group of medicines called “Other anti-acne preparations for topical use”; it is a medicine for external use (on the skin). Skinoren works against bacteria that play an essential role in causing acne (Propionibacterium acne). It also works by reducing the growth of certain skin cells (keratinocytes) that can clog the pores of the skin, thus reducing the formation of black spots (comedones) and purulent. It is indicated in the symptomatic treatment of acne vulgaris in adults and adolescents over 12 years of age. You should see a doctor if it gets worse or does not improve after 4 weeks of treatment.

How does it work?

The antimicrobial action and the direct influence on follicular hyperkeratosis form the basis of Skinoren’s therapeutic efficacy in the treatment of acne. Clinically, a significant decrease in both the density of colonization by Propionibacterium acnes and the fraction of free fatty acids in the lipids of the skin surface is observed. In vitro and in vivo, azelaic acid inhibits the proliferation of keratinocytes and normalizes the altered terminal epidermal differentiation processes that occur in acne. In the rabbit ear model, azelaic acid accelerates comedolytic of tetradecane-induced comedones.

What are the benefits of taking it?

Skinoren Cream uses include being indicated for the treatment for various skin conditions, such as severe acne (pimples), rosacea (red spots on the face, sometimes with visible papules, pustules, or veins), and hyperpigmentation (dark spots). Skinoren smoothes the outer layer of the skin so that the pores become clogged less quickly and excess oil from the skin (sebum) can drain better. The cream also reduces inflammation and discoloration on the skin or even allows it to disappear completely. This makes the skin clean and smooth again.

How do I use it and its dosage?

Always take this medicine exactly as described by your doctor, pharmacist or nurse tells you. If in doubt, ask your doctor, pharmacist, or nurse.

Cutaneous use.

Adults and adolescents over 12 years: before applying for this medicine, you should thoroughly clean the skin with plenty of water, and then dry it. You can also use a mild skin cleansing agent.

The recommended dose is:

Apply to the affected areas of the skin 2 times a day (morning and night), with a gentle massage. Approximately 2.5 cm of cream is sufficient for the entire area of ​​the face.

Wash your hands after each application.

If you experience significant skin irritation when applying for this medicine, you should reduce the amount of cream per application and/or the frequency of application to once a day or both until the irritation disappears. Or you can stop the treatment for a few days if necessary. Consult your doctor if irritation persists.

The duration of treatment varies from person to person and also depends on the severity of the skin condition. It is important that you use this medicine regularly throughout the treatment period.

In general, in patients with acne, a marked improvement is usually seen after approximately 4 weeks of treatment. To achieve optimal results, it is recommended to use Skinoren for several months, it could be used continuously for up to 12 months, depending on the result obtained.

Use in children and adolescents

When the cream is applied in adolescents (between 12 and 18 years of age) it is not necessary to modify the doses in relation to adults. The safety and efficacy of Skinoren in children below 12 years of age have not been established.

Side effects & precautions

Like all medicines, Skinoren can cause side effects, although not everybody gets them.

The most frequently observed adverse reactions include burning, itching (itching) or erythema (redness) at the application site.

The following side effects listed below are based on data from clinical studies and post-marketing experience with Skinoren cream. Adverse effects are listed according to the frequency of occurrence in which they have been reported:

Very common (May affect more than 1 in 10 patients):

  • Burning, itching (itching) and erythema (redness)

Common (May affect up to 1 in 10 patients):

  • pain, exfoliation (peeling, peeling), dryness, discoloration and irritation.

Uncommon (May affect up to 1 in 100 patients):

  • seborrhea (excessively oily skin), skin depigmentation (discoloration), acne, paraesthesia (tingling, tickling, prickling or burning sensation), dermatitis, malaise and edema (swelling) at the application site.

Rare (May affect up to 1 in 1,000 patients):

hypersensitivity to the active substance, cheilitis (inflammation of the corner of the lips), rash, heat, vesicles (small fluid-filled blister), eczema and ulcers.


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