What is Progynova?
Progynova is indicated in hormone replacement therapy (HRT) for the treatment of menopausal symptoms (period of time in which reproductive function and menstruation cease in a woman), natural or surgically caused (castration), e.g. ex. hot flushes, night sweats, urogenital disorders (atrophic vulvovaginitis). If you have your uterus intact, the administration of estrogens, as in the case of Progynova, must always be accompanied by the sequential administration of a progestogen.
How does it work?
The active substance, synthetic 17-estradiol, is chemically and biologically identical to human endogenous estradiol. It replaces the loss of estrogen production that occurs during menopause and relieves menopause symptoms. Ovulation is not inhibited during the use of Progynova, and endogenous hormone production is hardly affected.
What are the benefits of taking it?
Progynova is indicated as Hormone Replacement Therapy (HRT). Contains estrogen, a female hormone. After menopause, the ovaries stop producing this hormone. Progynova is used to treat menopausal symptoms such as hot flashes, night sweats, or vaginal dryness. Progynova is also used in the prevention of osteoporosis in postmenopausal women who are at high risk for fractures and who cannot use other osteoporosis treatments. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............. ........................
How do I use it and its dosage?
Always use Progynova patches exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.
Your doctor should always consider giving the lowest dose and the shortest duration of treatment. If you think that Progynova’s action is too strong or weak, tell your doctor or pharmacist.
Adult women, including the elderly.
If you are hysterectomised (your uterus is partially or completely removed), you can start treatment at any time.
If you have an intact uterus and still have menstrual cycles, treatment should start within 5 days after the start of menstruation by combining Progynova with a progestogen.
If you do not have menstrual periods, your menstrual periods are very infrequent, or you are in the postmenopausal period, treatment can be started by combining Progynova with a progestogen at any time, provided that a possible pregnancy.
Posology
Unless the doctor tells you otherwise, treatment is started by taking two Progynova 1 mg tablets without chewing daily, after a meal. After a certain time, your doctor may reduce the dose to one daily 1 mg tablet.
After 6 months of treatment, it is recommended to stop the medication to check if the discomfort still persists.
Administration
After each 20-day treatment cycle, the coated tablets may be paused, usually for a week or less (cyclic HRT), or the coated tablets may be continued without interruption (continuous HRT). In the latter case, a new container is started directly at the end of the previous one.
Combined guideline:
If you have an intact uterus, the concomitant use of an appropriate progestogen is recommended for 10-14 days every 4 weeks (combined sequential HRT) or with each estrogen-coated tablet (continuous combined HRT).
Your physician should make an adequate provision to facilitate and ensure proper adherence to the recommended combination regimen.
The tablets should be taken without chewing, with some liquid.
It does not matter what time of day you take the tablet, but once you have selected a specific time, you should keep it every day.
Adding a progestogen is not recommended in hysterectomised women unless there is a previous diagnosis of endometriosis.
Change from other HRT treatments (cyclical, continuous sequential, or combined continuous):
if you switch from other HRT treatments, you must end your treatment cycle before starting Progynova treatment.
If you think that Progynova’s action is too strong or weak, tell your doctor or pharmacist.
Side effects & precautions
Like all medicines, this medicine can cause side effects, although not everybody gets them. For more information, please refer to the Patient information leaflet. The following diseases occur more frequently in women who use HRT compared to women who do not take HRT:
- breast cancer
- abnormal growth or cancer of the inner wall of the uterus (endometrial hyperplasia or cancer)
- ovarian cancer
- blood clots in the veins of the legs or lungs (venous thromboembolism)
- coronary heart disease
- stroke
- probable memory loss if HRT has been started after 65 years of age.
The possible adverse effects are listed below, according to the part of the organism that they affect and their frequency of appearance, which have been reported in users of different oral preparations of hormone replacement therapy.
Common side effects (may affect up to 1 in 10 people):
- Weight gain, weight decrease
- Headache (headache)
- Abdominal pain, nausea
- Skin rash, itching (itching)
- Vaginal bleeding including spotting
Uncommon Progynova side effects (may affect up to 1 in 100 people):
- Hypersensitivity (allergic) reaction
- Depressive mood
- Dizziness
- Visual disturbances
- Palpitations
- Dyspepsia (difficult digestion)
- Erythema nodosum (inflammation of the skin with the appearance of nodules, usually located on the legs)
- Urticaria
- Breast pain, tenderness in the breasts
- Edema (fluid retention)
Rare Progynova side effects (may affect up to 1 in 1,000 people):
- Anxiety, increased libido (sexual desire), decreased libido
- Migraine
- Intolerance to contact lenses
- Bloating, vomiting
- Hirsutism (excessive hair growth), acne
- Muscle cramps
- Dysmenorrhea (painful menstruation), vaginal discharge, premenstrual-like syndrome, breast enlargement
- Fatigue
Lillian Papenfuss –
Fabulous service everytime… Thank you thats all l can say
Kate Whitney –
I know this is an older HRT but at the moment it is working great for me. I have used it for quite a number of years so for me the it is has worked a treat.
Lillian Papenfuss –
I have used this hrt for many years …its my life line !
Derek Oneal –
Handy to get these online during lockdown
Clayton Reed –
I now only take 1/2 a mg a day, and it makes all the difference, no flushes that ruin your life, you feel everything is as it should be ” normal.”
Douglas Hastings –
I’ve been using it for years and I’m fine. More than fine.
Judith Fillmore –
A good alternative to my preferred brand now unavailable.
Terry Fong –
i USUALLY use Progynova 2mg but as this currently is not available I am “doubling up” on the 1mg size until hopefully this situation will ease. It has served me well over many years for HRT symptoms etc. Also |I rate the Oxford online pharmacy as first class every time I have ordered. Many thanks Mrs L.A. ARMSTRONG
Erika Thomas –
Really fantastic products and quick service. Same price as a prescription but no hassle of having to go any were to pick up the prescription then go to the pharmacy
Anthony Bonilla –
Very good will definitely be buying again
Floyd Whipkey –
Just what I needed to continue to enjoy life, Thank you
Gale Johnson –
Great product, his product is excellent for preventing my hot flushes and night sweats …Perfect for my condition
Paula Mascorro –
Excellent for relieving symptoms, Have used these for quite a while now, and find them very effective
David John –
Used for many years and is excellent.
Amy Re –
Although the 2mg was sold out they kindly sent me the 1 mg Thank you
John Hicks –
GIVES ME A PERFECT HORMONE BALANCE
Thomas Eslinger –
Does what I want it to do thank you.
Ted Webb –
Terrible sticky label on packaged tablets. Removing it to reveal dates to be taken left nasty sticky residue
Ruby Whitlatch –
Excellent for relieving menopausal syptoms.Zero side effects
Judith Zimmerman –
This product is fantastic and new research papers reveal that although most women take for post menopause it also helps to correct and help post menapausal epilepsy in some cases. I live a good life due to this medication. Oxford online are an excellent company – they listen take into account people as individuals l am soo grateful for their help and professional support..
Ronald Hettinger –
Not a lot you can say. It’s excellent but out of stock. Replaced by 1 mg tablets.
George Eaton –
I have been taking these for quite a few years now & have found them to be very effective.